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Simple & efficient lab testing for health professionals.

Great Plains - CMI30

OAT (Organic Acid Test)

The Essentials Urine Turn Around Time: 10 Days
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Description

Great Plains organic acid test includes 76 urinary metabolites that provide a comprehensive snapshot of a patient’s overall health as the initial screening test and is useful for discovering underlying causes for chronic illness.
Includes biomarkers for:


• Intestinal Microbial Overgrowth
• Oxalate Metabolites
• Glycolytic Cycle Metabolites
• Mitochondrial Makers (Kreb Cycle)
• Neurotransmitter Metabolites
• Folate Metabolism
• Ketone and Fatty Acid Oxidation
• Nutritional Markers
• Indicators of Detoxification
• Amino Acid Metabolites


Organic acids are chemical compounds excreted in the urine that are products of metabolism. Metabolism is the sum of chemical reactions in living beings by which the body builds new molecules and breaks down molecules to eliminate waste products and produce energy.

Organic acids are most commonly analysed in urine because they are not extensively reabsorbed in the kidney tubules after glomerular filtration. Thus, organic acids in urine are often present at 100 times their concentration in the blood serum and thus are more readily detected in urine. This is why organic acids are rarely tested in blood or serum.

Methodology

Organic acids are measured by a combination of gas or liquid chromatography linked with mass spectrometry

When should I use

The Great Plains Organic Acids Test (OAT) assess 10 key areas and includes 76 organic acids to provide a comprehensive metabolic snapshot of a patient’s overall health. Organic Acids Test is an essential profile for anyone seeking additional information related to underlying gut derived bacterial and fungal toxins, as well as evaluating for less known metabolic imbalances such as mitochondrial function. It is not a test limited to just a few conditions, but instead can be done on anyone dealing with a complicated and chronic health problem.

• GI conditions – IBS, Dysbiosis/Yeast
• Chronic Fatigue/ Fibromyalgia
• Autism/AD(H) D/ Asperger Syndrome
• Mental health
• Low energy
• Depression/ Stress/Anxiety
• Eating disorders
• Cognitive decline
• Nutrient deficiencies
• Headaches/Migraines
• Joint/muscle pain
• Brain Fog
• Skin issues

Other Details

Other tests to consider
MOAT CMI32
GPL TOX + OAT CMI43
ENVIROtox Complete Panel GPL01
OAT + Mycotxoin GPL03
  • 2-Hydroxybutyric
  • 2-Hydroxyhippuric
  • 2-Hydroxyisocaproic
  • 2-Hydroxyisovaleric
  • 2-Hydroxyphenylacetic
  • 2-Oxo-4-methiolbutyric
  • 2-Oxoglutaric
  • 2-Oxoisocaproic
  • 2-Oxoisovaleric
  • 3-Hydroxy-3-methylglutaric (CoQ10)
  • 3-Hydroxybutyric
  • 3-Hydroxyglutaric
  • 3-Indoleacetic
  • 3-Methyl-2-oxovaleric
  • 3-Methylglutaconic
  • 3-Methylglutaric
  • 3-Oxoglutaric
  • 4-Cresol (C. di­fficile)
  • 4-Hydroxybenzoic
  • 4-Hydroxybutyric
  • 4-Hydroxyhippuric
  • 4-Hydroxyphenyllactic
  • 5-Hydroxyindolacetate (5HIAA)
  • 5-Hydroxymethyl-2-furoic
  • Acetate
  • Acetoacetic
  • Aconitic
  • Adipic
  • Arabinose
  • Ascorbic (Vitamin C)
  • Carboxycitric
  • Citramalic
  • Citric
  • Creatinine
  • DHPPA (beneficial bacteria)
  • Dihydroxyphenylacetic (DOPAC)
  • Ethylmalonic
  • Fumaric
  • Furan-2
  • Furancarbonylglycine
  • Glutaric (Vitamin B2 (Riboflavin))
  • Glutathione
  • Glyceric
  • Glycolic
  • Hippuric
  • Homogentisic
  • Homovanillate (HVA)
  • HPHPA (Clostridia marker)
  • HVA/DOPAC Ratio
  • HVA/VMA Ratio
  • Kynurenic
  • Lactic
  • Malic
  • Malonic
  • Mandelic
  • Methylcitric (Biotin)
  • Methylmalonic Acid (MMA)
  • Methylsuccinic
  • N-Acetylaspartic
  • N-Acetylcysteine (Glutathione precursor and chelating agent)
  • Orotic
  • Oxalic
  • Pantothenic (Vitamin B5)
  • Phenyllactic
  • Phenylpyruvic
  • Phosphoric
  • Pyridoxic (Vitamin B6)
  • Pyroglutamic
  • Pyruvic
  • Quinolinic
  • Sebacic
  • Suberic
  • Succinic
  • Tartaric
  • Thymine
  • Tricarballylic
  • Uracil
  • Vanilmandelate (VMA)
  • Vitamin B2
  • Vitamin B6
  • Vitamin C

View Details

Description

Great Plains organic acid test includes 76 urinary metabolites that provide a comprehensive snapshot of a patient’s overall health as the initial screening test and is useful for discovering underlying causes for chronic illness.
Includes biomarkers for:


• Intestinal Microbial Overgrowth
• Oxalate Metabolites
• Glycolytic Cycle Metabolites
• Mitochondrial Makers (Kreb Cycle)
• Neurotransmitter Metabolites
• Folate Metabolism
• Ketone and Fatty Acid Oxidation
• Nutritional Markers
• Indicators of Detoxification
• Amino Acid Metabolites


Organic acids are chemical compounds excreted in the urine that are products of metabolism. Metabolism is the sum of chemical reactions in living beings by which the body builds new molecules and breaks down molecules to eliminate waste products and produce energy.

Organic acids are most commonly analysed in urine because they are not extensively reabsorbed in the kidney tubules after glomerular filtration. Thus, organic acids in urine are often present at 100 times their concentration in the blood serum and thus are more readily detected in urine. This is why organic acids are rarely tested in blood or serum.

Methodology

Organic acids are measured by a combination of gas or liquid chromatography linked with mass spectrometry

When should I use

The Great Plains Organic Acids Test (OAT) assess 10 key areas and includes 76 organic acids to provide a comprehensive metabolic snapshot of a patient’s overall health. Organic Acids Test is an essential profile for anyone seeking additional information related to underlying gut derived bacterial and fungal toxins, as well as evaluating for less known metabolic imbalances such as mitochondrial function. It is not a test limited to just a few conditions, but instead can be done on anyone dealing with a complicated and chronic health problem.

• GI conditions – IBS, Dysbiosis/Yeast
• Chronic Fatigue/ Fibromyalgia
• Autism/AD(H) D/ Asperger Syndrome
• Mental health
• Low energy
• Depression/ Stress/Anxiety
• Eating disorders
• Cognitive decline
• Nutrient deficiencies
• Headaches/Migraines
• Joint/muscle pain
• Brain Fog
• Skin issues

Other Details

Other tests to consider
MOAT CMI32
GPL TOX + OAT CMI43
ENVIROtox Complete Panel GPL01
OAT + Mycotxoin GPL03

View Analytes

  • 2-Hydroxybutyric
  • 2-Hydroxyhippuric
  • 2-Hydroxyisocaproic
  • 2-Hydroxyisovaleric
  • 2-Hydroxyphenylacetic
  • 2-Oxo-4-methiolbutyric
  • 2-Oxoglutaric
  • 2-Oxoisocaproic
  • 2-Oxoisovaleric
  • 3-Hydroxy-3-methylglutaric (CoQ10)
  • 3-Hydroxybutyric
  • 3-Hydroxyglutaric
  • 3-Indoleacetic
  • 3-Methyl-2-oxovaleric
  • 3-Methylglutaconic
  • 3-Methylglutaric
  • 3-Oxoglutaric
  • 4-Cresol (C. di­fficile)
  • 4-Hydroxybenzoic
  • 4-Hydroxybutyric
  • 4-Hydroxyhippuric
  • 4-Hydroxyphenyllactic
  • 5-Hydroxyindolacetate (5HIAA)
  • 5-Hydroxymethyl-2-furoic
  • Acetate
  • Acetoacetic
  • Aconitic
  • Adipic
  • Arabinose
  • Ascorbic (Vitamin C)
  • Carboxycitric
  • Citramalic
  • Citric
  • Creatinine
  • DHPPA (beneficial bacteria)
  • Dihydroxyphenylacetic (DOPAC)
  • Ethylmalonic
  • Fumaric
  • Furan-2
  • Furancarbonylglycine
  • Glutaric (Vitamin B2 (Riboflavin))
  • Glutathione
  • Glyceric
  • Glycolic
  • Hippuric
  • Homogentisic
  • Homovanillate (HVA)
  • HPHPA (Clostridia marker)
  • HVA/DOPAC Ratio
  • HVA/VMA Ratio
  • Kynurenic
  • Lactic
  • Malic
  • Malonic
  • Mandelic
  • Methylcitric (Biotin)
  • Methylmalonic Acid (MMA)
  • Methylsuccinic
  • N-Acetylaspartic
  • N-Acetylcysteine (Glutathione precursor and chelating agent)
  • Orotic
  • Oxalic
  • Pantothenic (Vitamin B5)
  • Phenyllactic
  • Phenylpyruvic
  • Phosphoric
  • Pyridoxic (Vitamin B6)
  • Pyroglutamic
  • Pyruvic
  • Quinolinic
  • Sebacic
  • Suberic
  • Succinic
  • Tartaric
  • Thymine
  • Tricarballylic
  • Uracil
  • Vanilmandelate (VMA)
  • Vitamin B2
  • Vitamin B6
  • Vitamin C

View Sample Reports