Arrow Fat Left Icon Arrow Fat Right Icon Arrow Right Icon Cart Icon Close Circle Icon Expand Arrows Icon Facebook Icon Instagram Icon Twitter Icon Youtube Icon Hamburger Icon Information Icon Down Arrow Icon Mail Icon Mini Cart Icon Person Icon Ruler Icon Search Icon Shirt Icon Triangle Icon Bag Icon Play Video
Jump here to Public Website Click here to return to our public website
Homocysteinemia (MTHFR)
Homocysteinemia (MTHFR)
Homocysteinemia (MTHFR)
Homocysteinemia (MTHFR)

Laboratoire Reunis

Homocysteinemia (MTHFR)

Homocysteinemia (MTHFR) The enzyme methylenetetrahydrofolate reductase (MTHFR) plays an important... View Full Description

£121.00

Product code: GEN44

Category: CardioMetabolic

Category: Genetics



    Homocysteinemia (MTHFR)

    The enzyme methylenetetrahydrofolate reductase (MTHFR) plays an important role in the metabolism of folate. It catalyses the irreversible reduction of 5, 10-methylenetetrahydrofolate to 5-methylenetetrahydrofolate. This enzymatic reaction is necessary for the synthesis of methionine via the remethylation of homocysteine. If the enzymatic activity is reduced the serum homocysteine is increase. The hyperhomocysteinemia is an independent risk factor of thromboembolic disease, as well as lesions.

    There is a relationship between the neural tube defects in newborns and high homocysteine levels in the mother. Genetic variations of the MTHFR gene lead to the synthesis of a thermolabile enzyme that has a diminished activity, predisposing to severe side effects during treatment with methotrexate. In such cases, the detection of the polymorphism of the MTHFR gene allows and assessment of the relative risk for side effects before treatment.

    Turnaround time: 27 WORKING DAYS

    Product code: GEN44

    Category: CardioMetabolic

    Category: Genetics



      Homocysteinemia (MTHFR)

      The enzyme methylenetetrahydrofolate reductase (MTHFR) plays an important role in the metabolism of folate. It catalyses the irreversible reduction of 5, 10-methylenetetrahydrofolate to 5-methylenetetrahydrofolate. This enzymatic reaction is necessary for the synthesis of methionine via the remethylation of homocysteine. If the enzymatic activity is reduced the serum homocysteine is increase. The hyperhomocysteinemia is an independent risk factor of thromboembolic disease, as well as lesions.

      There is a relationship between the neural tube defects in newborns and high homocysteine levels in the mother. Genetic variations of the MTHFR gene lead to the synthesis of a thermolabile enzyme that has a diminished activity, predisposing to severe side effects during treatment with methotrexate. In such cases, the detection of the polymorphism of the MTHFR gene allows and assessment of the relative risk for side effects before treatment.

      Turnaround time: 27 WORKING DAYS